| 发明名称 |
OLIGONUCLEOTIDE COMPOSITIONS FOR THE TREATMENT OF ALZHEIMER'S DISEASE |
| 摘要 |
The invention relates to the identification of microRNAs whose expression is diminished in neurodegenerative disorders. In particular, the identified microRNAs can be used for the downregulation of the beta-secretase (BACE1) in mammalian brain and hence for the treatment of Alzheimer's disease.
|
| 申请公布号 |
US2010204309(A1) |
申请公布日期 |
2010.08.12 |
| 申请号 |
US20080450698 |
申请日期 |
2008.04.21 |
| 申请人 |
VIB VZW;KATHOLIEKE UNIVERSITEIT LEUVEN, K.U. LEUVEN R & D |
发明人 |
HERBERT SEBASTIEN;DE STROOPER BART |
| 分类号 |
A61K31/7088;A61P25/28;C07H21/04;C12Q1/68 |
主分类号 |
A61K31/7088 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
|
| 地址 |
|
