METHOD FOR COATING MICROSPHERES ONTO A FLEXIBLE MATERIAL

摘要

The invention relates to a method for coating polymer microspheres laden with one or more active substances onto a flexible material without melting, comprising the following steps: a) selecting a porous crosslinked polymer; b) incorporating a liquid lipophilic composition at room temperature and containing at least one active substance into the polymer by heating at a temperature higher by 1 to 5°C than the glass transition temperature of the polymer in order to obtain laden microspheres; c) placing the laden microspheres on the flexible material; d) heating the flexible material with the laden microspheres at a temperature higher by 1 to 10°C than the polymer melting temperature; e) cooling the flexible material impregnated with the laden microspheres. The coated flexible material of the invention is laden with one or more active substances having a therapeutic, dermatological cosmetic or olfactory effect and the diffusion is controlled on the basis of the polymers used for making the microspheres and on the nature of the active substances.