摘要 |
<P>PROBLEM TO BE SOLVED: To provide a Codon-optimized nucleic acid which encodes apo-clytin-II protein, can remarkably improve the light-emitting activity of clytin-II, and can prominently facilitate the detection of an intracellular calcium flow. <P>SOLUTION: This Codon-optimized nucleic acid encodes apo-clytin-II protein having a specific amino acid sequence or a mutant thereof. A recombinant host cell has the Codon-optimized nucleic acid. The apo-clytin-II protein is expressed with the Codon-optimized nucleic acid. <P>COPYRIGHT: (C)2010,JPO&INPIT |