发明名称 |
CYCLIC INHIBITORS OF 11BETA-HYDROXYSTEROID DEHYDROGENASE 1 |
摘要 |
This invention relates to novel compounds of an 11 ß-HSD1 inhibitor disclosed herein, pharmaceutically acceptable salts thereof, and pharmaceutical compositions thereof, which are useful for the therapeutic treatment of diseases associated with the modulation or inhibition of 11/3-HSD1 in mammals. The invention further relates to pharmaceutical compositions of the novel compounds and methods for their use in the reduction or control of the production of Cortisol in a cell or the inhibition of the conversion of cortisone to Cortisol in a cell.
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申请公布号 |
CA2750517(A1) |
申请公布日期 |
2010.08.12 |
申请号 |
CA20102750517 |
申请日期 |
2010.02.03 |
申请人 |
VITAE PHARMACEUTICALS, INC. |
发明人 |
CLAREMON, DAVID A.;ZHUANG, LINGHANG;LEFTHERIS, KATERINA;YE, YUANJIE;SINGH, SURESH B.;TICE, COLIN M. |
分类号 |
C07D487/04;A61K31/437;A61K31/4985;A61P3/00 |
主分类号 |
C07D487/04 |
代理机构 |
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主权项 |
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地址 |
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