发明名称 |
FLUORESCENT SOLVATOCHROMIC PIGMENT |
摘要 |
<p>Provided is a novel fluorescent solvatochromic pigment that (1) has ionic terminals readily enabling use on a hydrophilic surface or in a polar solvent; (2) can be efficiently excited by an ordinary argon laser (488 nm); (3) shifts emission wavelengths with changes in polarity; and (4) can effectively stain a biological tissue, such as a cell. When pyridinium groups were introduced to the electron-withdrawing groups of a neutral fluorescent solvatochromic pigment (JP 2008-291210 A) to synthesize a fluorescent solvatochromic pigment, it was discovered that this fluorescent solvatochromic pigment showed a strong fluorescent wavelength response to changes in the polarity of a hydrophilic surface and that a fluorescent solvatochromic pigment modified to become a cationic pigment can be used to stain a cell and monitor the behavior thereof.</p> |
申请公布号 |
WO2010090265(A1) |
申请公布日期 |
2010.08.12 |
申请号 |
WO2010JP51624 |
申请日期 |
2010.02.04 |
申请人 |
NATIONAL UNIVERSITY CORPORATION HOKKAIDO UNIVERSITY;YAMADA KOJI;YAMAGISHI YUTAKA;AYABE TOKIYOSHI;SON SANG-HYUN;AOYAGI MAIKO;TAIRA TOSHIO |
发明人 |
YAMADA KOJI;YAMAGISHI YUTAKA;AYABE TOKIYOSHI;SON SANG-HYUN;AOYAGI MAIKO;TAIRA TOSHIO |
分类号 |
C09B57/00;C07D409/04;C09K9/02;C09K11/06;C12N5/00;C12Q1/02 |
主分类号 |
C09B57/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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