发明名称 FLUORESCENT SOLVATOCHROMIC PIGMENT
摘要 <p>Provided is a novel fluorescent solvatochromic pigment that (1) has ionic terminals readily enabling use on a hydrophilic surface or in a polar solvent; (2) can be efficiently excited by an ordinary argon laser (488 nm); (3) shifts emission wavelengths with changes in polarity; and (4) can effectively stain a biological tissue, such as a cell. When pyridinium groups were introduced to the electron-withdrawing groups of a neutral fluorescent solvatochromic pigment (JP 2008-291210 A) to synthesize a fluorescent solvatochromic pigment, it was discovered that this fluorescent solvatochromic pigment showed a strong fluorescent wavelength response to changes in the polarity of a hydrophilic surface and that a fluorescent solvatochromic pigment modified to become a cationic pigment can be used to stain a cell and monitor the behavior thereof.</p>
申请公布号 WO2010090265(A1) 申请公布日期 2010.08.12
申请号 WO2010JP51624 申请日期 2010.02.04
申请人 NATIONAL UNIVERSITY CORPORATION HOKKAIDO UNIVERSITY;YAMADA KOJI;YAMAGISHI YUTAKA;AYABE TOKIYOSHI;SON SANG-HYUN;AOYAGI MAIKO;TAIRA TOSHIO 发明人 YAMADA KOJI;YAMAGISHI YUTAKA;AYABE TOKIYOSHI;SON SANG-HYUN;AOYAGI MAIKO;TAIRA TOSHIO
分类号 C09B57/00;C07D409/04;C09K9/02;C09K11/06;C12N5/00;C12Q1/02 主分类号 C09B57/00
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