发明名称 |
AMINOSÄUREAUSTAUSCHMUTANTEN VON INTERLEUKIN 13 |
摘要 |
This invention provides mutant hIL13 molecules include those made by substituting one or more of the amino acid residues that occur in the alpha-helix regions of native hIL13 with various other amino acid residues. Multiply mutated forms of hIL13 conjugated to cytotoxins are used to preferentially target diseased cells over non-diseased cells. |
申请公布号 |
DE60142479(D1) |
申请公布日期 |
2010.08.12 |
申请号 |
DE2001642479 |
申请日期 |
2001.08.24 |
申请人 |
THE PENN STATE RESEARCH FOUNDATION UNIVERSITY PARK |
发明人 |
DEBINSKI, WALDEMAR |
分类号 |
C07K14/54;C12N15/09;A61K38/00;A61K47/48;A61P11/06;A61P35/00;A61P37/08;A61P43/00;C07K16/24;C12N5/06 |
主分类号 |
C07K14/54 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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