| 摘要 |
An aqueous composition comprising a therapeutic protein further characterized in that (i) the pH of the composi-tion is adjusted to be between about 5.9 and 6.3, preferably about 6.1; (ii) the composition comprises at least one displaced buffer having a pKa within 1 to 3 pH units of the pH of the composition such as lactate and TRIS; (iv) the osmolarity of the composition is between 150 - 500 mOsm/L.
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