摘要 |
<p>A method for identifying a subject being at risk for or having a chronic inflammatory disease, fibrillinopathy, atherosclerosis, or coronary artery disease is provided. The method may include determining the concentration of GrA and/or GrB in a blood or serum sample from said subject; and comparing the concentrations to the corresponding concentration in a control sample, wherein an elevated concentration of GrA and/or GrB may be indicative of a chronic inflammatory disease, fibrillinopathy, atherosclerosis, or coronary artery disease. The method may further include identifying concentrations of fibrinogen, elastin and/or fibrillin.</p> |
申请人 |
THE UNIVERSITY OF BRITISH COLUMBIA |
发明人 |
GRANVILLE, DAVID;CRUZ, RANI;CHAMBERLAIN, CIARA;BOIVIN, WENDY;MCMANUS, BRUCE |