发明名称 |
STIMULATION OF ANTI-TUMOR IMMUNITY USING DENDRITIC CELL/TUMOR CELL FUSIONS AND ANTI-CD3/CD28 |
摘要 |
The invention is concerned with fusions of dendritic cells and with tumor or cancer cells. Also provided are methods of making and using these cell fusions, including methods of adoptive immunotherapy as well as methods of stimulating anti-tumor immunity using fused cells and anti-CD3/CD28 antibodies. |
申请公布号 |
EP2215220(A1) |
申请公布日期 |
2010.08.11 |
申请号 |
EP20080846621 |
申请日期 |
2008.11.07 |
申请人 |
DANA-FARBER CANCER INSTITUTE, INC.;BETH ISRAEL DEACONESS MEDICAL CENTER |
发明人 |
AVIGAN, DAVID;KUFE, DONALD |
分类号 |
C12N5/12;A61K39/00;C12N5/16;G01N33/00 |
主分类号 |
C12N5/12 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|