发明名称 REVERSIBLE MODIFICATION OF MEMBRANE INTERACTION
摘要 An process for the reversible modification of membrane interaction of a compound is described. Modification of membrane interaction can be used to facilitate delivery of molecules to cells in vitro and in vivo. The described modifiers, which are used to reversibly inactivate the membrane active compounds, can also be utilized as cross-linkers or to reverse the charge of a molecule.
申请公布号 EP1506218(A4) 申请公布日期 2010.08.11
申请号 EP20030755460 申请日期 2003.05.23
申请人 MIRUS BIO CORPORATION 发明人 ROZEMA, DAVID, B.;WOLFF, JON, A.;WAKEFIELD, DARREN;EKENA, KIRK;HAGSTROM, JAMES, E.
分类号 C07D307/60;A61K38/00;A61K45/00;A61K47/48;A61K48/00;C07K7/06 主分类号 C07D307/60
代理机构 代理人
主权项
地址