发明名称 |
Method for the detection of the in-vivo activity of neurotrypsin, use of the method and use of the C-terminal 22-kDa fragment of agrin as biomarker in diagnosis and monitoring of neurotrypsin-related disturbances |
摘要 |
Method for the detection of the in-vivo activity of neurotrypsin wherein the amount of the 22-kDa-fragment of agrin is measured in a sample taken from a patient and the measured amount of the 22-kDa-fragment of agrin in the sample is used to calculate the activity of neurotrypsin, use of the method for diagnosis and monitoring of neurotrypsin-related disturbances and use of the 22-kDa-fragment of agrin as biomarker for neurotrypsin-related disturbances. |
申请公布号 |
EP1990420(B1) |
申请公布日期 |
2010.08.11 |
申请号 |
EP20070009398 |
申请日期 |
2007.05.10 |
申请人 |
NEUROTUNE AG;UNIVERSITY OF ZURICH |
发明人 |
SONDEREGGER, PETER;HETTWER, STEFAN;STEPHAN, ALEXANDER;MIYAI, KAZUMASA;KUNZ, BEAT |
分类号 |
C12Q1/37 |
主分类号 |
C12Q1/37 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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