发明名称 |
A METHOD OF DIAGNOSING NEOPLASMS |
摘要 |
<p>The present invention relates generally to nucleic acid molecules, the RNA and protein expression profiles of which are indicative of the onset, predisposition to the onset and/or progression of a neoplasm. More particularly, the present invention is directed to nucleic acid molecules, the expression profiles of which are indicative of the onset and/or progression of a large intestine neoplasm, such as an adenoma or an adenocarcinoma. The expression profiles of the present invention are useful in a range of applications including, but not limited to, those relating to the diagnosis and/or monitoring of colorectal neoplasms, such as colorectal adenocarcinomas. Accordingly, in a related aspect the present invention is directed to a method of screening a subject for the onset, predisposition to the onset and/or progression of a neoplasm by screening for modulation in the expression profile of one or more nucleic acid molecule markers.</p> |
申请公布号 |
EP2215261(A1) |
申请公布日期 |
2010.08.11 |
申请号 |
EP20080843297 |
申请日期 |
2008.10.23 |
申请人 |
CLINICAL GENOMICS PTY LTD;COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION |
发明人 |
LAPOINTE, LAWRENCE, CLARENCE;DUNNE, ROBERT;YOUNG, GRAEME, P.;MOLLOY, PETER;PEDERSEN, SUSANNE;BROWN, GLENN, SOUTHWELL;GRAHAM, LLOYD, DOUGLAS |
分类号 |
C12Q1/68 |
主分类号 |
C12Q1/68 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|