发明名称 |
NUCLEIC ACID SAMPLE PREPARATION BY EXCLUSION OF DNA |
摘要 |
Devices and methods are provided for separation of nucleic acids from waste materials in a biological sample, and then reacting the separated nucleic acids. In some embodiments, the methods comprise mixing a cell lysate having nucleic acids and waste materials with a waste-binding matrix to capture the cellular waste materials from the lysate. The waste-binding matrix can comprise hydrophilic and/or hydrophobic size- exclusion, ion-exchange particles. In some embodiments, the device comprises a substrate comprising a fluid processing pathway in which nucleic acid sample preparation occurs prior to a downstream genotyping reaction. |
申请公布号 |
EP2170922(A4) |
申请公布日期 |
2010.08.11 |
申请号 |
EP20080768775 |
申请日期 |
2008.06.25 |
申请人 |
LIFE TECHNOLOGIES CORPORATION |
发明人 |
LAKDAWALLA, ABIZAR, A.;COX, DAVID, MAURICE |
分类号 |
C07H21/00 |
主分类号 |
C07H21/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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