CARBOXYLIC ACID DERIVATIVES THAT INHIBIT THE BINDING OF INTEGRINS TO THEIR RECEPTORS
摘要
A method for the inhibition of the binding of .alpha.4.beta.1 integrin to its receptors, for example VCAM-1 (vascular cell adhesion molecule-1) and fibronectin; compounds that inhibit this binding; pharmaceutically active compositions comprising such compounds; and to the use of such compounds either a above, or in formulations for the control or prevention of diseases states in which .alpha.4.beta.1 is involved.
申请公布号
CA2366800(C)
申请公布日期
2010.08.10
申请号
CA20022366800
申请日期
2002.01.07
申请人
TEXAS BIOTECHNOLOGY CORPORATION
发明人
BIEDIGER, RONALD J.;CHEN, QI;HOLLAND, GEORGE W.;KASSIR, JAMAL M.;LI, WEN;MARKET, ROBERT V.;WU, CHENGDE;DECKER, RADFORD E.;LI, JIAN;SCOTT, IAN L.
