| 摘要 |
FIELD: medicine. ^ SUBSTANCE: invention refers to medicine, specifically to a composition for treating dermatoses. The pharmaceutical composition for treating skin affections contains mometazone furoat as an active ingredient, and a hydrophobic phase, a hydrophilic phase, a mat additive, macrogol cetostearate, glyceryl monostearate and cetostearyl alcohol as adjuvants. The hydrophobic phase represents vaseline and white wax. The hydrophilic phase represents hexylene glycol, phosphoric acid and water. The mat additive represents aluminium starch octenylsuccinate and titanium dioxide. The pharmaceutical composition is presented in soft dosage form, preferentially as cream. The method for preparing the composition involves slurrying of the mat additive in fused vaseline, addition of glyceryl monostearate, cetostearyl alcohol, macrogol cetostearate and white wax to suspension, and emulsification in the prepared mixture of mometazone furoate solution in the hydrophilic phase. ^ EFFECT: new composition is characterised by high pharmacological activity, storage-stability, good packing extrusion, high degree of uniformity and optimum pH. ^ 8 cl, 1 tbl |
