发明名称 |
System, device and method for detection of several individual analytes in a solution, and a disposable flow cell for use therein |
摘要 |
A system, device and method for detection of several individual analytes in a test solution aliquot (83) with an array of individually operated piezoelectric crystal microbalances are described. The system comprises a connecting station (100) that receives a plurality of individually specific piezoelectric crystal microbalance flow-trough cells (10), each containing a piezoelectric crystal (50) carrying electrodes (56,62) and a coating (66,46) exposing a first member of an interaction pair specific for an individual analyte being a second member of the interaction pair. Flowing means (70) flows a solution (75) and the test solution aliquot (83) to and through a cell compartment of each of the cells (10) via the connecting station (100). Power and measurement means (130) oscillate the piezoelectric crystal(s) (50). A change in oscillating characteristics of the crystal(s) (50), following interaction between the first and second members of the interaction pair, detects presence of the individual analyte(s). Further, disposable flow cells (10) for use in an array of individually operated piezoelectric crystal microbalances (112) is described.
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申请公布号 |
US7771657(B2) |
申请公布日期 |
2010.08.10 |
申请号 |
US20050517321 |
申请日期 |
2005.08.23 |
申请人 |
BIOSENSOR APPLICATIONS SWEDEN AB |
发明人 |
MAANSSON PER;ANDERSSON HENRIK;SMITH JAN;JENSEN KJELD;AASTRUP TEODOR |
分类号 |
G01N21/00;C12Q1/00;C12Q1/68;G01N1/00;G01N5/02;G01N27/00;G01N29/036;G01N31/00;G01N33/22;G01N33/53;G01N33/567 |
主分类号 |
G01N21/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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