PURPOSE: A calpain inhibitor containing N-benzyloxycarbonyl-Val-Leu-leucinal is provided to protect nerve by calpain inhibition and to prevent or treat Alzheimer disease and Parkinson's disease. CONSTITUTION: A calpain inhibitor with nerve protection effect contains N-benzyloxycarbonyl-Val-Leu-leucinal as an active ingredient. The nerve protection is treatment or prevention of ischemic brain injury or neuropathic disease. Ischemic diseases are cerebral hemorrhage, or spinal cord injury. A health food for nerve protection contains N-benzyloxycarbonyl-Val-Leu-leucinal as an active ingredient.
申请公布号
KR20100088390(A)
申请公布日期
2010.08.09
申请号
KR20090007582
申请日期
2009.01.30
申请人
UNIVERSITY OF ULSAN FOUNDATION FOR INDUSTRY COOPERATION
发明人
KIM, DONG HOU;YOON, SEUNG YONG;CHOI, JUNG EUN;CHOE, HAN SEOK