发明名称 6-SUBSTITUTED INDOLE-3-CARBOXYLIC ACID AMIDE COMPOUNDS HAVING SPHINGOSINE-1-PHOSPHATE (S1P) RECEPTOR ANTAGONIST BIOLOGICAL ACTIVITY.
摘要 <p>The invention provides compounds represented by the formula I, each of which compounds may have sphingosine-1 -phosphate receptor agonist and or antagonist biological activity : Formula (I) and wherein the variables Y, R4, n, o, A, A1, A2, X, Z, R1, R3, R2, p, q and r are as defined in the specification. These compounds are useful for treating a disease or condition selected from the group consisting of glaucoma, dry eye, angiogenesis, cardiovascular conditions and diseases, and wound healing.</p>
申请公布号 MX2010007588(A) 申请公布日期 2010.08.06
申请号 MX20100007588 申请日期 2008.07.10
申请人 ALLERGAN, INC. 发明人 RICHARD L. BEARD;TIEN T. DUONG;XIAOXIA LIU;JOHN E. DONELLO;HAIQING YUAN
分类号 C07D209/42;A61K31/404;A61P9/00;C07D405/04 主分类号 C07D209/42
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