| 发明名称 |
ENHANCEMENT OF IMMUNOGENICITY OF VIRUS VACCINE BY USE OF OPTIMIZED ANTIGEN GENE |
| 摘要 |
<P>PROBLEM TO BE SOLVED: To provide a virus vector vaccine exhibiting a high expression level of an antigen protein in a mammal cell. <P>SOLUTION: The virus vector vaccine is obtained by incorporating an antigen gene subjected to synonymous substitution for increasing the expression level in the mammal cell than that in the wild-type one. <P>COPYRIGHT: (C)2010,JPO&INPIT |
| 申请公布号 |
JP2010168288(A) |
申请公布日期 |
2010.08.05 |
| 申请号 |
JP20090010172 |
申请日期 |
2009.01.20 |
| 申请人 |
YOKOHAMA CITY UNIV |
发明人 |
SHIMADA MASARU;SHOJI MASAKI;OKUDA KENJI |
| 分类号 |
A61K48/00;A61K35/76;A61K39/21;A61P31/18;C12N15/09 |
主分类号 |
A61K48/00 |
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