发明名称 |
PROSTATE CANCER PROGRESSION INHIBITOR AND PROGRESSION INHIBITION METHOD |
摘要 |
<p>Disclosed is a prostate cancer progression inhibitor comprising 4-(4-cyano-2-[[2-(4-fluoro-1-naphthyl)propanoyl]amino]- phenyl)butyric acid, a salt or solvate of the compound, or a prodrug of the compound or the salt or solvate. 4-(4-Cyano-2-[[2-(4-fluoro-1-naphthyl) propanoyl]amino]-phenyl)butyric acid has an anti-proliferative activity and an activity to recover hormone responsiveness and the like in prostate cancer that acquires hormone resistance, and is therefore useful as a prostate cancer progression inhibitor.</p> |
申请公布号 |
WO2010087425(A1) |
申请公布日期 |
2010.08.05 |
申请号 |
WO2010JP51188 |
申请日期 |
2010.01.29 |
申请人 |
KYOTO UNIVERSITY;ONO PHARMACEUTICAL CO., LTD.;OGAWA OSAMU;TSUJIMOTO GOZOH;NAKAMURA EIJIRO;KAMBA TOMOMI;SHIMIZU YOSUKE;TERADA NAOKI;KANAJI TOSHIYA;MARUYAMA TAKAYUKI |
发明人 |
OGAWA OSAMU;TSUJIMOTO GOZOH;NAKAMURA EIJIRO;KAMBA TOMOMI;SHIMIZU YOSUKE;TERADA NAOKI;KANAJI TOSHIYA;MARUYAMA TAKAYUKI |
分类号 |
A61K31/277;A61K45/00;A61P13/08;A61P35/00;A61P43/00 |
主分类号 |
A61K31/277 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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