METHOD FOR SCREENING SUBSTANCE USEFUL AS THERAPEUTIC AGENT FOR PROSTATE CANCER

摘要

Disclosed is a method for screening a compound that is useful as a therapeutic agent for diseases associated with 17ßHSD type-5 and/or a therapeutic agent for cancer associated with 17ßHSD type-5, such as prostate cancer. Specifically disclosed is a method for screening a compound that is useful for the treatment of diseases associated with 17ßHSD type-5, which comprises transplanting a tumor cell into an immunodeficient mouse or the like to manifest a tumor, topically administering a steroid that is a starting material for the biosynthesis of a hormone to the tumor, and measuring the quantity of the hormone produced in the tumor.