发明名称 |
Modified Two-Component Gelation Systems, Methods of Use and Methods of Manufacture |
摘要 |
Compositions, methods of manufacture and methods of treatment for post-myocardial infarction are herein disclosed. In some embodiments, the composition includes at least two components. In one embodiment, a first component can include a first functionalized polymer and a substance having at least one cell adhesion site combined in a first buffer at a pH of approximately 6.5. A second component can include a second buffer in a pH of between about 7.5 and 9.0. A second functionalized polymer can be included in the first or second component. In some embodiments, the composition can include at least one cell type and/or at least one growth factor. In some embodiments, the composition(s) of the present invention can be delivered by a dual bore injection device to a treatment area, such as a post-myocardial infarct region.
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申请公布号 |
US2010196313(A1) |
申请公布日期 |
2010.08.05 |
申请号 |
US20100756092 |
申请日期 |
2010.04.07 |
申请人 |
ABBOTT CARDIOVASCULAR SYSTEMS INC. |
发明人 |
MICHAL EUGENE;TROLLSAS OLOF MIKAEL;BASU SHUBHAYU |
分类号 |
A61K38/20;A61K35/12;A61K38/16;A61K38/19;A61P9/10 |
主分类号 |
A61K38/20 |
代理机构 |
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地址 |
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