Hydrogen Sulfide Donating Polymers

摘要

Described herein are hydrogen sulfide (H2S) donating polymers and polymer systems suitable for coating or forming medical devices and methods for making and using the same. More specifically, described are H2S donating polymers comprising at least one monomer with at least one basic group that can be complexed with H2S to form a charged H2S complex. The H2S donating polymers can provide controlled release of H2S once implanted at or within the target surgical site. The H2S donating polymers can be coated onto a medical device, formed into a medical device or combined with one or more other polymers to form a polymer system.