发明名称 CROMOLYN DERIVATIVES AND RELATED METHODS OF IMAGING AND TREATMENT
摘要 Novel cromolyn analogs useful as imaging agents for detecting atherosclerotic plaques and for treating atherosclerosis and Alzheimer's Disease, and methods of making the cromolyn analogs, are disclosed. The cromolyn analogs have the general formula (I), or formula (II); wherein X is OH, C1-C6 alkoxyl, 18F, or 19F; Y and Z are independently selected from a C1-C6 alkyl, CpC6 alkoxyl, halogen, un-substituted or C1-C6 substituted amine, 18F, 19F, or H; and n is 1, 2, or 3; and wherein for structure (I), if n are both 1 and Y and Z are both H, X is not OH.
申请公布号 CA2751125(A1) 申请公布日期 2010.08.05
申请号 CA20102751125 申请日期 2010.01.29
申请人 THE GENERAL HOSPITAL CORPORATION 发明人 ELMALEH, DAVID R.;SHOUP, TIMOTHY
分类号 C07D405/12;A61K31/352;A61P9/10;A61P25/28 主分类号 C07D405/12
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