发明名称 |
Method for Predicting the Response of a Patient to Treatment with an Anti-TNF Alpha Antibody |
摘要 |
The present invention relates to a method for predicting the response of a patient to treatment with an anti-TNFα therapy, in particular an anti-TNFα antibody, the method comprising: (a) providing an in vitro sample of T cells from the patient; (b) exposing said T cells to an anti-TNFα therapy; and (c) determining whether regulatory T cells are induced in said sample of T cells wherein the induction of regulatory T cells indicates that the patient is likely to respond to treatment with said anti-TNFα therapy.
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申请公布号 |
US2010196402(A1) |
申请公布日期 |
2010.08.05 |
申请号 |
US20080601173 |
申请日期 |
2008.05.20 |
申请人 |
UCL BUSINES PLC |
发明人 |
EHRENSTEIN MICHAEL;MAURI CLAUDIA |
分类号 |
A61K39/395;A61P29/00;A61P37/00;C12Q1/02 |
主分类号 |
A61K39/395 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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