| 发明名称 |
Glycosaminoglycan-antagonising MCP-1 Mutants and Methods of Using Same |
| 摘要 |
Novel mutants of human monocyte chemoattractant protein 1 (MCP-1) with increased glycosaminoglycan (GAG) binding affinity and knocked-out or reduced GPCR activity compared to wild type MCP-1, and their use for therapeutic treatment of inflammatory diseases.
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| 申请公布号 |
US2010197583(A1) |
申请公布日期 |
2010.08.05 |
| 申请号 |
US20080670378 |
申请日期 |
2008.07.21 |
| 申请人 |
PROTAFFIN BIOTECHNOLOGIE AG |
发明人 |
KUNGL ANDREAS;PICCININI ANNA MARIA;WEBER CHRISTIAN |
| 分类号 |
A61K38/19;A61P29/00;C07H21/04;C07K14/52;C12N5/10;C12N15/63 |
主分类号 |
A61K38/19 |
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