| 发明名称 |
RECOMBINANT VACCINE VIRUSES EXPRESSING IL-15 AND METHODS OF USING THE SAME |
| 摘要 |
<p>The invention is directed to compositions capable of augmenting the immunogenicity of a vaccine. The composition, or adjuvant, is administered to a mammal in need thereof in sequential or concurrent combination with a vaccine antigen. In one preferred aspect, the adjuvant is provided in the form of a recombinant poxvirus vector, such as a vaccinia virus vector, which comprises a nucleic acid sequence encoding IL-15.</p> |
| 申请公布号 |
EP1575601(A4) |
申请公布日期 |
2010.08.04 |
| 申请号 |
EP20030814012 |
申请日期 |
2003.12.15 |
| 申请人 |
THE GOVERNMENT OF THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES |
发明人 |
PERERA, LIYANGE, P.;WALDMANN, THOMAS, A.;OH, SANG-KON;BERZOFSKY, JAY, A. |
| 分类号 |
A61K39/00;A61K39/21;A61K39/39;(IPC1-7):A61K35/00;C12N15/63;A61K48/00 |
主分类号 |
A61K39/00 |
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