发明名称 |
TREATMENT REGIME FOR PROLIFERATIVE DISORDERS |
摘要 |
<p>Provided herein are methods for treating or ameliorating a proliferative disorder in a subject. The method contains the steps of administering to the subject one dose of an immunosuppressive agent followed by administering to the subject one to five doses of a reovirus. The immunosuppressive agent is administered to the subject at least about 72 hours prior to administration of the reovirus. Also provided herein are methods for treating or ameliorating a proliferative disorder in a subject including the steps of administering to the subject an oncolytic virus and a B-cell modulating agent. Also provided are kits and pharmaceutical compositions containing an oncolytic virus and at least one B-cell modulating agent.</p> |
申请公布号 |
EP2211880(A1) |
申请公布日期 |
2010.08.04 |
申请号 |
EP20080841201 |
申请日期 |
2008.10.22 |
申请人 |
ONCOLYTICS BIOTECH INC. |
发明人 |
COFFEY, MATTHEW C.;THOMPSON, BRADLEY G. |
分类号 |
A61K35/76;A61K31/664;A61K39/15;A61K45/06;A61P35/00 |
主分类号 |
A61K35/76 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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