| 发明名称 |
USE OF OLIGONUCLEOTIDES WITH MODIFIED BASES AS ANTIVIRAL AGENTS AGAINST BOVINE PAPILLOMAVIRUS |
| 摘要 |
<p>The present invention relates to the use of oligonucleotides having modified nucleobases to inhibit gene expression and/or replication of viruses in a subject. The modified nucleobases may be mercapto-modified bases or hydroxy-modified nucleobases. It is contemplated that the oligonucleotides further comprise a nuclease complex which enhances anti-viral activity of the oligonucleotides.</p> |
| 申请公布号 |
EP2212420(A2) |
申请公布日期 |
2010.08.04 |
| 申请号 |
EP20080846868 |
申请日期 |
2008.11.05 |
| 申请人 |
BALTIC TECHNOLOGY DEVELOPMENT, LTD. |
发明人 |
SAARMA, MART;MERITS, ANDRES;KARELSON, MATI |
| 分类号 |
C12N15/113;A61K31/7115;A61P31/20;C07H21/00 |
主分类号 |
C12N15/113 |
| 代理机构 |
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