<p>An expandable medical device includes a plurality of elongated struts, forming a substantially cylindrical device which is expandable from a first diameter to a second diameter. A plurality of different beneficial agents may be loaded into different openings within the struts for delivery to the tissue. For treatment of conditions such as restenosis, different agents are loaded into different openings in the device to address different biological processes involved in restenosis and are delivered at different release kinetics matched to the biological process treated. The different agents may also be used to address different diseases from the same drug delivery device. In addition, anti-thrombotic agents may be affixed to at least a portion of the surfaces of the medical device for the prevention of sub-acute thrombosis. Primer layers may be used to ensure that the different agents remain affixed to the device as well as to each other.</p>
申请公布号
EP2213264(A1)
申请公布日期
2010.08.04
申请号
EP20100152030
申请日期
2010.01.28
申请人
CORDIS CORPORATION
发明人
PRICE, SYLVESTER;STANLEY, JAMES R L;LUK, ANDREW;SUN, YI-PING;DOOLEY, JOHN;GUY, LOUIS-GEORGES;KOVALCSIK, ROSE;BEAUDRY, DIANE;STEESE-BRADLEY, GARY;ROGERS, CAMPBELL