发明名称 |
AN INHALABLE DRY POWDER FORMULATION COMPRISING GLP-1 FOR USE IN THE TREATMENT OF HYPERGLYCEMIA AND DIABETES BY PULMONARY ADMINISTRATION |
摘要 |
<p>A method for preventing or reducing adverse effects such as profuse sweating, nausea and vomiting, which normally are associated with subcutaneous and intravenous administration of glucagon-like peptide 1 (GLP-1) therapy is provided. In particular, the method comprises the rapid administration of a GLP-1 formulation into the pulmonary circulation such as by inhalation, directly into pulmonary alveolar capillaries using a dry powder drug delivery system.</p> |
申请公布号 |
EP2211842(A2) |
申请公布日期 |
2010.08.04 |
申请号 |
EP20080841194 |
申请日期 |
2008.10.24 |
申请人 |
MANNKIND CORPORATION |
发明人 |
RICHARDSON, PETER;BAUGHMAN, ROBERT, A.;COSTELLO, DONALD |
分类号 |
A61K9/14;A61K31/495;A61K38/26;A61P3/10 |
主分类号 |
A61K9/14 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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