VACCINE COMPOSITIONS OBTAINED FROM STREPTOMYCES

摘要

THE INVENTION RELATES TO FIELD OF IMMUNOLOGY AND MORE SPECIFICALLY TO THE CONTROL OF INFECTIOUS DISEASES CAUSED BY MICROBACTERIA WHICH IS BASED ON THE USE OF VACCINES FOR THE PREVENTION OF SAID DISEASES. THE INVENTIVE VACCINES HAVE BEEN DEVELOPED WITH THE USE OF LIVE STRAINS OF STRPTOMYCES, WHICH MAYOR MAY NOT EXPRESS ANTIGENS OF M. TUBERCULOSIS AND HAVE DEMONSTRATED THEIR PROTECTIVE CAPACITY AGAINST THE THREAT BCG AND M.TUBERCULOSIS AFTER BEING ADMINISTRATED BY DIFFERENT ROUTES. THE INVENTION ALSO RELATES TO THE USE OF STRAINS OF STREPTOMYCES FOR THE EXPRESSION OF HETEROLOGOUS ANTIGENS OF VACCINAL INTEREST.