发明名称 |
MULTI-NUCLEATED CELL CLASSIFICATION AND MICRONUCLEI SCORING |
摘要 |
<p>Methods and systems for counting nuclei for cells in a cell-containing sample are disclosed. The methods comprise: receiving a raw image of the cell-containing sample; transforming the raw image into a segmented image comprising one or more nuclei clusters. The methods further comprise: for each of the one or more nuclei clusters, obtaining a convex hull of the nuclei cluster; locating any indentations on the nuclei cluster by comparing the nuclei cluster to the convex hull of the nuclei cluster; calculating a first nuclei count based on a tally of the indentations; and assigning the nuclei cluster to a cell among the plurality of cells. The methods further comprise: calculating a second nuclei count for each cell by totaling the first nuclei counts of its constituent nuclei clusters; and presenting a result based on the second nuclei count for at least one of the plurality of cells.</p> |
申请公布号 |
WO2010068799(A3) |
申请公布日期 |
2010.07.29 |
申请号 |
WO2009US67560 |
申请日期 |
2009.12.10 |
申请人 |
MDS ANALYTICAL TECHNOLOGIES (US) INC.;HONG, DIHUI;COHEN, AVRUM I. |
发明人 |
HONG, DIHUI;COHEN, AVRUM I. |
分类号 |
G06K9/00;G06K9/34;G06K9/48 |
主分类号 |
G06K9/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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