发明名称 |
Zusammensetzungen aus orthogonalen Lysyl-TRNA- und Aminoacyl-TRNA-Synthetasepaaren und deren Verwendung |
摘要 |
Compositions and methods of producing components of protein biosynthetic machinery that include orthogonal lysyl-tRNAs, orthogonal lysyl-aminoacyl-tRNA synthetases, and orthogonal pairs of lysyl-tRNAs/synthetases, which incorporate homoglutamines into proteins are provided in response to a four base condon. Methods for identifying these orthogonal pairs are also provided along with methods of producing proteins and homoglutamines using these orthogonal pairs. |
申请公布号 |
DE602004027770(D1) |
申请公布日期 |
2010.07.29 |
申请号 |
DE20046027770T |
申请日期 |
2004.07.07 |
申请人 |
THE SCRIPPS RESEARCH INSTITUTE, LA JOLLA |
发明人 |
ANDERSON, CHRISTOPHER J.;WU, NING;SANTORO, STEPHEN;SCHULTZ, PETER G. |
分类号 |
C12P21/00;C12N;C12N1/20;C12N9/00;C12P1/04 |
主分类号 |
C12P21/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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