METHOD FOR SCREENING INHIBITOR OF AMPK ACTIVITY

摘要

PURPOSE: A method for screening an inhibitor of AMPK activation is provided to select a material which suppresses inter-combination of AMPKγ1 and DNA-PKcs and to use as an anticancer drug. CONSTITUTION: A method for screening drug for suppressing cancer proliferation and/or metastasis or protecting nerve comprises: a step of treating a candidate material which suppresses inter-combination of AMPKγ1 and DNA-PKcs (experimental group); a step of measuring activation of inter-combination of AMPKγ1 and DNA-PKcs(positive control group) and inter-combination of the experimental group; and a step of selecting candidate material over the positive control group.