发明名称 CYCLOALKYLAMINES AS MONOAMINE REUPTAKE INHIBITORS
摘要 The invention relates to novel cyclohexylamine derivatives and their use in the treatment and/or prevention of central nervous system (CNS) disorders, such as depression, anxiety, schizophrenia and sleep disorder as well as methods for their synthesis. The invention also relates to pharmaceutical compositions containing the compounds of the invention, as well as methods of inhibiting reuptake of endogenous monoamines, such as dopamine, serotonin and norepinephrine from the synaptic cleft and methods of modulating one or more monoamine transporter.
申请公布号 US2010190861(A1) 申请公布日期 2010.07.29
申请号 US20100688474 申请日期 2010.01.15
申请人 发明人 SHAO LIMING;WANG FENGJIANG;MALCOLM SCOTT CHRISTOPHER;HEWITT MICHAEL CHARLES;BUSH LARRY R.;MA JIANGUO;VARNEY MARK A.;CAMPBELL UNA;ENGEL SHARON RAE;HARDY LARRY WENDELL;KOCH PATRICK;CAMPBELL JOHN E.
分类号 A61K31/135;A61P25/00;A61P25/24;C07C211/15;C07C215/48 主分类号 A61K31/135
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