A METHOD FOR PROTECTING DNA DAMAGE USING PIG3

摘要

PURPOSE: A composition and method for protecting DNA damage using PIG3 are provided to suppress cytotoxicity and to relate to normal recognition in DNA damage. CONSTITUTION: An anti-cancer aid contains an inhibitor for expression or activation of PIG3(p53-inducible gene 3). The PIG3 has an amino acid sequence of sequence number 1. The inhibitor for expression of PIG3 is an antisense nucleotide which complementarily binds to mRNA of PIG3 gene, small interfering RNA(siRNA) or small hairpin RNA(shRNA). The inhibitor for expression or activation of PIG3 treats and prevents cancer by administering to cancer cells. A cosmetic composition for anti-aging contains PIG3 gene construct as an active ingredient. The PIG3 gene has a nucleotide sequence of sequence number 2.