| 发明名称 |
ENHANCEMENT OF TRANSGENE EXRESSION FROM VIRAL BASED VACCINE VECORS BY EXPRESSION OF SUPPRESSORS OF THETYPE I INTERFERON RESPONSE |
| 摘要 |
<p>Viral-based vectors are genetically engineered to express inhibitors of the anti-viral immune system (e.g. inhibitors of the type I interferon response) in order to enhance transgene expression. The transgenes may encode antigens or other therapeutic agents.</p> |
| 申请公布号 |
KR20100085905(A) |
申请公布日期 |
2010.07.29 |
| 申请号 |
KR20107006357 |
申请日期 |
2008.08.29 |
| 申请人 |
AERAS GLOBAL TB VACCINE FOUNDATION |
发明人 |
SADOFF JERALD C.;FULKERSON JOHN;FAKRUDDIN JAMILUDDIN MOHAMAD;STONE MICHELE R.;ANANTHA RAVI |
| 分类号 |
C12N15/85;A61K39/00;A61P35/00 |
主分类号 |
C12N15/85 |
| 代理机构 |
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代理人 |
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