| 发明名称 |
STABILIZED FC POLYPEPTIDES WITH REDUCED EFFECTOR FUNCTION AND METHODS OF USE |
| 摘要 |
A method of producing Fc-containing polypeptides, such as antibodies, having stabilized Fc regions is provided, together with stabilized Fc polypeptides produced according to these methods as well as methods of using such antibodies as therapeutics.
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| 申请公布号 |
CA2750533(A1) |
申请公布日期 |
2010.07.29 |
| 申请号 |
CA20102750533 |
申请日期 |
2010.01.22 |
| 申请人 |
BIOGEN IDEC MA INC. |
发明人 |
REYES, CHRISTOPHER L.;CHAN, ERIC;TAYLOR, FREDERICK R.;GARBER, ELLEN;MILLER, BRIAN ROBERT;DEMAREST, STEPHEN;GLASER, SCOTT |
| 分类号 |
C07K16/46;A61K39/395;C07K16/00;C12N15/00;C12N15/13 |
主分类号 |
C07K16/46 |
| 代理机构 |
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