TRANSFERT DE GÈNE IN VIVO ET EX VIVO DANS UN TISSU RÉNAL À L'AIDE DE VECTEURS ADÉNOVIRAUX N'EXPRIMANT PLUS DE GÈNES VIRAUX
摘要
<p>A method for treating a renal disease in a subject is disclosed. The method includes administering into a kidney of the subject with an effective amount of a gutless adenoviral vector containing a polynucleotide encoding a therapeutic agent. The gutless adenoviral vector contains the nucleotide sequence of SEQ ID NO : 13 or SEQ ID NO : 15 and expresses the therapeutic agent in a kidney tissue of the subject.</p>