发明名称 |
CD20-binding polypeptide compositions |
摘要 |
A CD20-binding polypeptide composition comprising a combination of a modified heavy chain variable region polypeptide and a modified light chain variable region polypeptide. The combination can be (a) a modified 2B8 antibody heavy chain variable region polypeptide of SEQ ID NO: 48; and a modified 2B8 antibody light chain variable region polypeptide of SEQ ID NO: 49; or (b) a modified Leu16 antibody heavy chain variable region polypeptide of SEQ ID NO: 50; and a modified Leu16 antibody light chain variable region polypeptide of SEQ ID NO: 51. |
申请公布号 |
AU2004264372(B2) |
申请公布日期 |
2010.07.29 |
申请号 |
AU20040264372 |
申请日期 |
2004.08.16 |
申请人 |
MERCK PATENT GMBH |
发明人 |
STEPHEN WILLIAMS;FRANCIS J. CARR;STEPHEN D. GILLIES |
分类号 |
A61P37/00;C07K16/28;C07K16/30;C12N15/13 |
主分类号 |
A61P37/00 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|