Provided herein are modified OB-fold domains having desired properties; methods of producing libraries of modified OB-fold domains; the libraries of modified OB-fold domains produced by such methods; methods for screening such libraries of modified OB-fold domains for desired biological activities; and the modified OB-fold domains identified from such libraries. Provided herein are modified OB-fold domains obtainable from Pyrobaculum aerophilum that exhibit modified binding interactions.
申请公布号
ZA200810836(B)
申请公布日期
2010.07.28
申请号
ZA20080010836
申请日期
2007.05.25
申请人
OBODIES LIMITED
发明人
ARCUS, VICKERY LAURENCE;STEEMSON, JOHN DUDRAND;BAAKE, MATTHIAS