Diagnostic method for transmissible spongiform encephalopathies

摘要

A method of diagnosis of a transmissible spongiform encephalopathy (TSE) or the possibility thereof in a subject suspected of suffering from the TSE, which comprises determining a test amount of a polypeptide in a sample of body fluid taken from the subject, wherein the polypeptide is differentially contained in the body fluid of TSE-infcctcd subjects and non-TSE-infcctcd subjects, and is Cystatin C; and determining whether the test amount is consistent with a diagnosis of TSE.