Induction of tolerogenic phenotype in mature dendritic cells
摘要
The present invention relates to the use of a CD45 binding molecule to modulate the function of Dendritic cells. In particular the present invention relates to the use of a CD45 binding molecule to induce tolerogenic dendritic cells, useful in the treatment of diseases or disorders such as autoimmune diseases, transplant rejection.
申请公布号
ZA200908089(B)
申请公布日期
2010.07.28
申请号
ZA20090008089
申请日期
2009.11.17
申请人
NOVARTIS A.G.;FONDAZIONE CENTRO SAN RAFFAELE DEL MONTE TABOR