Production process for NSAID-containing lozenges, their compositions, their medicinal use

摘要

A process for producing a pharmaceutical lozenge formulation comprising the steps of:
(a) providing a liquid composition comprising a salt of a non=steroidal anti-inflammatory drug (NSAID salt) and a solvent system, (b) providing a molten lozenge-forming composition, (c) mixing the liquid composition with the molten lozenge-forming composition, and (d) forming the resulting mixture into lozenges each containing a therapeutically effective amount of said NSAID salt/NSAID mixture. The present application discloses the corresponding NSAID-containing lozenge compositions and their use for the manufacture of a medicament for treating sore throat.