发明名称 Wet granulation tableting method using aqueous dispersion of low-substituted hydroxypropyl cellulose
摘要 Provided is a method for preparing a tablet having high tablet hardness and an excellent disintegration property even if low-substituted hydroxypropyl cellulose is added in a relatively small amount. More specifically, provided is a method for preparing a tablet comprising steps of granulating while spraying an aqueous dispersion of low-substituted hydroxypropyl cellulose having a degree of hydroxypropoxyl group substitution ranging from 5 to 16% by weight to a tablet-forming composition and tableting the resulting granules.
申请公布号 EP2210591(A2) 申请公布日期 2010.07.28
申请号 EP20100151595 申请日期 2010.01.25
申请人 SHIN-ETSU CHEMICAL CO., LTD. 发明人 MARUYAMA, NAOSUKE
分类号 A61K9/16;A61K9/20;A61K31/167 主分类号 A61K9/16
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