| 摘要 |
<p>Preparing zwitterionic adsorbent material for liquid chromatography, comprises: (a) reacting a silane compound (I) with either a sulfonic acid compound (II) or a sulfonic acid compound (III); and (b) reacting the reaction product obtained in (a) with a solid carrier comprising polymeric or inorganic carriers. Preparing zwitterionic adsorbent material for liquid chromatography, comprises: (a) reacting a silane compound of formula (R 2>)-Si(R 3>)(R 1>)-R 4>-X (I) with either a sulfonic acid compound of formula (Y1-R 5>-S(=O)(OR 6>)=O) (II) or sulfonic acid compound of formula (III); and (b) reacting the reaction product obtained in (a) with a solid carrier comprising polymeric or inorganic carriers. R 1>-R 3>optionally substituted 1-20C alkoxy, 1-20C aralkoxy, 1-20C alkyl or 1-20C alkenyl or halide; R 4>, R 5>optionally substituted 1-20C alkylene, 1-20C alkenylene or 6-20C arylene; R 6>H, optionally substituted 1-20C alkyl, 1-20C alkenyl or 6-20C arylene; R 7>optionally substituted 2-20C alkylene or 2-20C alkenylene; either X : pri-, sec- or tert amino (when the reaction of silane compound (I) with sulfonic acid compound (III)); or X or Y1 : pri-, sec- or tert- amino, halide or oxirane (when the reaction of silane compound (I) with sulfonic acid compound (II)). An independent claim is also included for a zwitterionic adsorbent for liquid chromatography, prepared by the above method. [Image].</p> |
