| 发明名称 |
FUSED QUINOXALINE DERIVATIVES AS INHIBITORS OF AKT ACTIVITY |
| 摘要 |
The present invention is directed to compounds comprising a ring-fused quinoxalinyl moiety which inhibit the activity of Akt, a serine/threonine protein kinase. The invention is further directed to chemotherapeutic compositions containing the compounds of this invention and methods for treating cancer comprising administration of the compounds of the invention.
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| 申请公布号 |
CA2481241(C) |
申请公布日期 |
2010.07.27 |
| 申请号 |
CA20032481241 |
申请日期 |
2003.04.04 |
| 申请人 |
MERCK & CO., INC. |
发明人 |
LINDSLEY, CRAIG W.;ZHAO, ZHIJIAN |
| 分类号 |
C07D487/04;A61K31/498;A61K31/4985;A61K45/00;A61P35/00;A61P43/00;C07D241/36;C07D401/14;C07D487/02;C07D519/00;C07D519/04 |
主分类号 |
C07D487/04 |
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