摘要 |
<P>PROBLEM TO BE SOLVED: To develop a compound useful as an inhibitor of a protein kinase. Ž<P>SOLUTION: The present invention relates to compounds of formula (I), or a pharmaceutically acceptable salt thereof, wherein: W and X are each independently oxygen or sulfur; A is nitrogen, CH, C-CN, or C-(1-3C aliphatic); and R<SP>1</SP>and R<SP>2</SP>are bound together to form a ring. These compounds are useful as inhibitors of JAK kinases, particularly for the treatment of an autoimmune disease, a neurodegenerative disorder, or a hematologic malignancy. Ž<P>COPYRIGHT: (C)2010,JPO&INPIT Ž
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