发明名称 CYCLOALKYL LACTAM DERIVATIVES AS INHIBITORS OF 11-BETA-HYDROXYSTEROID DEHYDROGENASE 1
摘要 The present invention discloses compounds of Formula I: (I) having 11beta-HSD type 1 antagonist activity, as well as methods for preparing such compounds. In another embodiment, the invention discloses pharmaceutical compositions comprising compounds of Formula I, as well as the use of the Formula I and compositions as medicaments to treat diabetes, hyperglycemia, obesity, hypertension, hyperlipidemia, Syndrome X, and other conditions associated with hyperglycemia.
申请公布号 US2010184764(A1) 申请公布日期 2010.07.22
申请号 US20100727871 申请日期 2010.03.19
申请人 ELI LILLY AND COMPANY 发明人 AICHER THOMAS DANIEL;CHICARELLI MARK JOSEPH;HINKLIN RONALD JAY;TIAN HONGQI;WALLACE OWEN BRENDAN;ALLEN JOHN GORDON;CHEN ZHAOGEN;MABRY THOMAS EDWARD;MCCOWAN JEFFERSON RAY;SNYDER NANCY JUNE;WINNEROSKI, JR. LEONARD LARRY
分类号 A61K31/40;A61K31/4439;A61K31/454;A61K31/4545;A61K31/496;A61K31/497;A61K31/506;A61K31/5377;C07D207/26;C07D207/273;C07D401/04;C07D401/10;C07D401/14;C07D403/10;C07D413/12 主分类号 A61K31/40
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